【摘要】 目的观察比较前列腺素E1脂微球载体制剂(LipoPGE1)和丹参对老年人血小板聚集率的影响。方法将38例老年心、脑血管疾病患者,在均衡原则下随机分成两组。一组予前列腺素E1脂微球载体制剂(LipoPGE1)10μg/天,共14天,另一组予丹参针剂12ml/天,共14天,比较两者对血小板聚集率的影响。结果前列腺素E1组降低血小板聚集(P<0.01),丹参组降低血小板聚集率(P<0.05)。结论前列腺素E1脂微球载体制剂(LipoPGE1)和丹参都能抑制血小板聚集,而LipoPGE1更有效,无一例发生静脉炎。但从效价比出发,丹参更适合国情。更多还原

【Abstract】 Objective To compare the effects on platelet aggregation rate(PAgT) between prostaglandin E1 and danshen. Methods 38 aged patients with cardiovascular or cerebrovascular diseases participated the study. On the principle of balance, they were divided into 2 groups at random. One had received the treatments of Lipo PGE1 10μg/day for two weeks. The other had treated with danshen 12ml/day for two weeks. The platelet aggregation rates were recorded before and after treatment. Results In Lipo PGE1 group, the PAgT reduced(P< 0.01),whereas in the danshen group the PAgT also reduced(P< 0.05). Conclusions Either Lipo PGE1 or danshen were effective on the PAgT. Lipo PGE1 had a better effect, but danshen was more suitable for the general population because of its cheaper price.更多还原