【摘要】 目的　探讨原发性高血压 (EH )患者血压变异性与靶器官损害、血压增高的程度及年龄的关系。方法　对65例EH患者及 40例正常人 (对照组 )进行 2 4h动态血压监测 ,以测定的血压标准差作为血压变异性指标。结果　EH组血压变异性明显大于对照组 ,Ⅱ、Ⅲ期EH患者血压变异性明显大于Ⅰ期EH患者 ;EH患者血压变异性随血压水平的增加而逐渐增大 ,年龄≤ 5 5岁者 ,其血压变异性随年龄的增加而增大 ,年龄 >5 5岁者 ,其血压变异性不再随继续增加。结论　EH患者血压变异性明显增加 ,且靶器官损害越重 ,血压值越高 ,在一定范围内年龄越大则血压变异性越大更多还原

【Abstract】 Objectives To observe the relationship between blood pressure (BP) variability and the target organ damage, the extent of BP increasing, age in patients with primary hypertension. Methods 40 normal controls and 65 patients with primary hypertension were undergone 24 hours ambulatory blood pressure monitoring. The BP variability (BPV) was determined by standard deviation(s) from mean blood pressure during the 24 hours. Results BPV in patients primary hypertension was higher than that in normal controls ( P <0 01) BPV in patients with stage Ⅱ and Ⅲ primary hypertension were higher than that in those with stage Ⅰ ( P <0 01). BPV increased with age in patients less than 55 years old, but did not in those more than 55 years old. Conclusions Patients with primary hypertension have increased BPV. Furthermore, the BPV increased with the extent of target organ damage. BP value and, to some extent, the age of the patients.更多还原