【摘要】 目的:探讨环磷酸腺苷葡甲胺(心先安)对缓慢性心律失常的疗效及价值。方法:将60例缓慢性心律失常(心室率<50次/分)患者随机分为治疗组和对照组,两组分别静脉点滴心先安和静脉点滴山莨菪碱(654-2)注射液,两周后比较两者临床、心电图的变化。结果:(1)临床疗效:治疗组和对照组总有效率为88.9％和48.5％,两组差异性有显著差异(P<0.01);(2)体表心电图:治疗组和对照组总有效率为85.2％和48.5％,统计学比较有明显差异(P<0.01)。结论:心先安治疗缓慢性心律失常有明显疗效,近期疗效好,副作用少,其远期效果有待观察。更多还原

【Abstract】 Objective: To evaluate the curative effect and clinical value of meglumine cycli adenylate (MCA) in the slowness arrhythmia. Methods: 60 patients with the slowness arrhythmia were divided into two groups for treatment and control group, 27 patients were given MCA by intravenous driping for tow weeds as treatment group, the other 33 patients were given anisodamini hydrobremidum (654-2)for tow weeks as control group. Compared the changes of clinical expression and electrocardiogram (ECG) study in tow groups with randomized comparative analysis. Results: 1. Clinical curative effect: The total rate of the MCA group was 88.9%, while that of the 654-2 group was 48.5%. There was significant difference between them (P<0.01). 2. ECG: the total rate of the treatment group was 85.2%, and that control group was 48.5%. There was signifcant difference between them (P<0.01). Conclusions: There is an evident short-term, curative effect of MCA in slowness arrhythmia without side effect, hut the long-term effect remains to be observe.更多还原