【摘要】 目的　探讨生长抑素施他宁在胆源性急性胰腺炎中的治疗作用。方法　将 12 6例胆源性胰腺炎患者随机分为二组 ,治疗组 62例 ,对照组 64例 ,治疗组用施他宁治疗 7～ 10d ,观察并发症发生、住院时间和死亡率。结果　两组在年龄、性别、病因及疾病严重程度上无差别。与对照组相比 ,治疗组并发症发生率较低。住院时间明显缩短 ,P <0 .0 5 ;治疗组死亡 8例 ,对照组有死亡 10例。结论　生长抑素施他宁治疗胆源性重症急性胰腺炎有效 ,可减缓病情发展 ,缩短住院时间 ,改善预后。更多还原

【Abstract】 Objective To determine the efficiency of somatostatin in treatment of patient with choledochitis acute pancreatitis.Methods 126 patients with choledochitis acute pancreatitis were selected and randomly assigned to treatment either with or without stilamin (6 mg per day). The end points of study included: complication rate (adult respiratory distress syndrome, sepsis, renal failure, pseudocyst, and abscess), length of hospital stay, and mortality.Results The two groups were matched with regard to age, sex, etiology, and severity of disease. The complication rate was lower in the treatment group compared with the control (group with regard to sepsis 24 compared with 71 percent,P<0.05) and ARDS (25 compared with 68 percent, P<0.05). The hospital stay was shorter in the treatment group compare with the control group (18.2 compare with 32.3 days, P<0.05). Death occurred in 8 patients in the treatment group and 10 patients in the control group.Conclusion The results suggest that somatoatatin(stilamin) may have a beneficial effect in the treatment of patient with choledochitis acute pancreatitis.更多还原