【摘要】 目的 :探讨中枢神经系统结核感染诊断。方法 :回顾性分析经尸检证实的 69例中枢神经系统结核感染病例。结果 :生前误诊 3 5例 ,误诊率 5 0 73 %。尸检发现脑膜病变为主 ,脑实质、脑室、脑血管、脊髓均受累。临床表现除脑膜刺激症、颅高压征 ,可有中枢神经系统局灶损害症状。颅高压是主要的死因 (61/ 69,88 4% )。结论 :中枢神经系统结核感染临床表现与结核病变性质、部位密切相关 ,认识其临床表现和病理特点有助提高诊断率更多还原

【Abstract】 Aim:To investigate the diagnosis of the central nervous system tuberculosis. Methods:69 cases of the central nervous system tuberculosis proved by autopsy were reviewed.Results:35 cases were misdiagnosed before death, the misdiagnosis rate was 50.73%. The main lesions were located in the meninges, brain parenchyma, brain ventricles, cerebral vascularity and spina. Besides signs of meningitis and intracranial hypertension, other clinical signs included focal neurological signs. The principal cause of death was intracranial hypertension. Conclusion:Clinical manifestations of central nervous system tuberculosis were related to the location and the pathological changes of tuberculosis. It is helpful to understand the clinicopathologic classifications for the diagnosis.更多还原