【摘要】 探讨临床监测HBVpreS1-Ag对乙肝患者诊断和预后的意义。对 10 0例乙型病毒性肝炎患者HBV血清标志物、HBV -DNA及preS1-Ag进行定量、定性跟踪监测并加以临床分析。 10 0例患者中HBsAg阳性者 91例 ,preS1-Ag阳性者 5 7例 ,HBeAg阳性者 4 3例 ,HBV -DNA阳性者 5 6例 ,preS1-Ag阳性率与HBV -DNA相似且略高于HBeAg。preS1-Ag比HBeAg更为精确地反映了HBV在人体内感染和复制的情况 ,动态监测 preS1-Ag的变化有助于临床评估急慢性肝炎的治疗效果及预后更多还原

【Abstract】 To study the clinical significance of detecting HBV preS 1-Ag on diagnosis and prognosis in HB patients. Make continuously quantity and quality detection and clinic analysis to 100 HB patients selected randomly In 100 HB patients, HBsAg, preS 1-Ag, HBeAg and HBV-DNA the positive patients were 91,57,43 and 56, respectively. The positive rate of preS 1-Ag was similar to that of HBV-DNA but a little higher than that of HBeAg. Compared with HBsAg preS 1-Ag can reflect the situation of inflection and reproduction of HBV in vivo more accurately. and clinical dynamic observation to preS 1-Ag will be useful for clinical evaluation to the effect and prognosis of acute and chronic hepatitis.更多还原