【摘要】 观察大蒜素对腺泡内肺动脉高压 (PHT)是否具有阻抑效应 ,在常压缺氧条件下 ,选用 4 2只大鼠 ,分正常组、缺氧组和缺氧加大蒜素组 ,分别在 15天和 30天测右心室收缩压 ,并观察其变化。结果显示大蒜素能降低肺动脉压。从而提示大蒜素具有预防缺氧性肺动脉压升高的作用 ,为该药防治肺动脉高压提供了有利的实验依据更多还原

【Abstract】 The inhibitory action of garlicin on remodeling of intra-acinar pulmonary arteries under pulmonary hypertension was studied.42 rats were fed in hypoxic environment under normal atmospheric pressure (10%O 2 10 hours/day)and divided into control group and hypoxia with garlicin group.On the 15th and 30th day of hypoxia,right ventricular systalic pressure was measured.Garlicin could decrease the pulmonary arteries pressure.Therefore,garlicin may play an important role in inhibiting pulmonary hypertpension.更多还原