【摘要】 大量的体内、体外实验表明,几丁聚糖及其衍生物具有良好的生物粘附性,能促进药物吸收,是非常有前景的药物吸收促进剂。讨论了几丁聚糖及其衍生物促进药物吸收作用的机制、影响因素,以及发展趋势。更多还原

【Abstract】 Chitosan and its derivatives are widely used in biopharmaceutical field as carriers for gene,oral administration of vaccines and drugs.Considerable in vitro and in vivo experiments reveal that chitosan and its derivatives are promising drug absorption enhancers.Mechanism and influencing factors of drug absorption enhancement by chitosan are reviewed, and urgent research topics are suggested.更多还原