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经导管肝动脉化疗栓塞治疗结直肠癌肝转移瘤

Transcatheter hepatic artery chemo-embolization for liver metastasis from colorectal carcinomas

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【作者】 王煊金导泉易竹筠朱锦秀何晓明

【Author】 WANG Xuan, JIN Daoquan, YI Zhujun, et al. The No.1 Hospital of Huaian, Jiangsu 223300, China

【机构】 江苏省淮安市第一人民医院江都市人民医院 223300223300

【摘要】 目的 总结经导管肝动脉化疗栓塞治疗结直肠癌肝转移瘤的效果。方法  42例结直肠癌肝转移者 ,其中单纯灌注化疗 14例 ,化疗栓塞 2 8例。经肝动脉灌注化疗药物 ,碘油药物乳剂和明胶海绵栓塞。结果 完全缓解 (CR) 2例 (4 .8% ) ,部分缓解 (PR) 2 0例 (4 7.6 % ) ,无变化 (NC) 18例(4 2 .9% ) ,进展 (PD) 2例 (4 .8% ) ,有效率 (CR +PR) 5 2 .4% (2 2 / 42 )。平均生存期为 16 .4个月。 0 .5、1和 2年的生存率分别为 90 .5 %、6 6 .7%和 2 3.8%。结论 经导管肝动脉化疗栓塞治疗结直肠癌肝转移是一种有效的方法

【Abstract】 Objective To analyse the clinical effectiveness of transcatheter hepatic artery chemo embolization on hepatic metastasis from colorectal carcinomas.Methods 42 cases were divided into 2 groups:simple chemotherapy group ( n =14), chemotherapy and embolization group ( n =28). After catheter was selectively inserted into hepatic artery, and then followed by chemotherapy, lipiodol and gelfoam infusion. Results CR 2 cases (4.8%); PR 20 cases (47.6%); NC 18 cases (42.9%); PD 2 cases (4.8%). The total anticancer effective rate (CR+PR) was 52.4%. The avevage survival time was 16.4 months. The 0.5 ,1 ,2 year survival rates were 90.5%, 66.7% and 23.8%, respectively.Conclusions Transcatheter hepatic artery chemo embolization is an effective method to treat liver metastasis of colorectal carcinomas. It is more effective than the simple chemotherapy.

【关键词】 结直肠癌肝转移瘤化疗栓塞
【Key words】 Colorectal carcinomaLiver metastasisChemotherapyEmbolization
  • 【文献出处】 介入放射学杂志 ,Journal of Interventional Radiology , 编辑部邮箱 ,2002年02期
  • 【分类号】R735.3
  • 【被引频次】8
  • 【下载频次】58
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