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米非司酮治疗子宫腺肌病的临床研究

Study on Mifepristone treatment in the Patients with adenomgosis.

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【作者】 吕俊光杨柳隋丽英位立群刘海宁

【Author】 Lu Junguang, Yang Liu,Sui Hying,et al. Weihai Hospital, Weihai, 264200.

【机构】 山东省威海市立医院妇产科山东省威海市立医院妇产科山东省威海市立医院妇产科 副主任医师 264200

【摘要】 目的:探讨低剂量米非司酮治疗子宫腺肌病的疗效。方法:采用低剂量米非司酮治疗子宫腺肌病患者62例,B超观察用药前后子宫与腺肌瘤的体积变化,监测用药前后促卵泡成熟素(FSH)、黄体生成素(LH)、泌乳素(PRL)、雌二醇(E2)、孕酮(P)、睾酮(T)水平。结果:用药前后子宫及腺肌瘤体积均有显著差异(P<0.01),FSH、LH、E2、P、T水平用药后均有不同程度的改变(P>0.05),PRL显著降低(P<0.05)。结论:低剂量米非司酮治疗子宫腺肌病,可使子宫与腺肌瘤的体积明显缩小,并消除和改善临床症状。

【Abstract】 Objective: To investigate the effect of low dose mifepristone treatment in the patients with adenomgosis. Methods;62 patients with adenomgosis were given low dose mifepristone. The changes in size of uterus and adenomgoma were checked before and after therapy,respectively. The levels of follicle stimulating hormone(FSH) ,luteinizing hormone (LH) ,prolactin(PRL) ,estradiol(E2),progesterone(P) , testosterone(T) were dectected simultaneously. Results:There was significant difference in uterine size and in adenomyomasize before and after mifepristone treatment (P <0. 01). The levels of FSH, LH, PRL,E2 ,P,T were decreased to certain degree. Conclusion ;Low dose mifepristone markedly reduced the size of uterus and adnomyoma and decreased the level of hormone in the body.

【关键词】 米非司酮治疗子宫腺肌病
【Key words】 Mifepristone Therapy Adenomyosis
  • 【文献出处】 中国计划生育学杂志 ,Chinese Journal of Family Planning , 编辑部邮箱 ,2002年11期
  • 【分类号】R711.74
  • 【被引频次】24
  • 【下载频次】75
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