【摘要】 目的　明确疫区主要宿主动物及疫区性质 ,为制定防制策略提供科学依据。方法　采用间接免疫荧光技术检测肾综合征出血热 (HFRS)病毒抗原和抗体 ,小型宿主动物密度调查采用夹夜法。结果　宿主动物野外以黑线姬鼠 (Apodemus agrarius,Aa)为优势种 ,其密度和带毒率均最高 ;住宅区以褐家鼠 (Ratlus norvegicus,Rn)为优势种 ,褐家鼠在 2 0世纪 80年代中后期至 90年代初带毒率较高 ,之后未检出 HFRS病毒抗原。结论　贵州省遵义县肾综合征出血热疫区是以黑线姬鼠为主要宿主动物和传染源 ;2 0世纪 80年代中后期疫区性质以姬鼠型为主的混合型 ,其余年代均为典型的姬鼠型更多还原

【Abstract】 Objective To study the main host animals and features of epidemic areas and to provide scientific data for controlling Hemorrhagic Fever with Renal Syndrome (HFRS). Methods Indirect Fluorescent Antibody Technic was used to test HV antigen and HV antibody in the small host animals’ lungs and sera. Results Apodemus agrarius(Aa) was the most common host among HFRS’s host animals in the field however the most common host animal in the house was Ratlus norvegicus(Rn), and positive rate of HV was high from 1985 to 1991, but after 1992 the antigen of HV in the Ra’s lung was negative. Conclusions The Aa is the main host animals and epidemic sources of HFRS in Zunyi, Guizhou.更多还原