【摘要】 目的 观察NO、ET₁在癫痫发作的即时血浆浓度的变化。方法 对精神疾病符合电休克（ECT）治疗标准患者,ECT诱发癫痫发作进行治疗,在治疗前后5分钟测定患者血浆NO、ET₁。结果癫痫发作后NO、ET₁均有明显升高（P<0.05）。结论 NO可能参与了癫痫的发生、扩散,ET₁在缺氧状态下体内会加速释放,更加剧了组织缺氧。更多还原

【Abstract】 To probe the concentrations changing of NO and ET1 in plasma around epileplic attack. Methods In patients according with electro- shock treatment ( ECT) standar, with ECT inducing episptic attack,then treating. The concentrations of NO and ET1 were detected during 5 minutes before and after treatment. Results The concentrations of NO and ET1 increased obviously after epileplic attack.Conclu-sio NO is the main factor which causing epilepsy attack a A proliferation. ET1 increases in hypoxia state and aggravates tissue anoxia.更多还原