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当归多糖对放射损伤小鼠红细胞免疫功能和造血功能的保护作用

Protective Effect of Angelica Polysaccharide on the Function of Erythrocyte Immunity and Hematopoiesis in Mice Damaged by Radiation

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【作者】 洪艳; 刘煜敏; 熊小红; 张渝侯; 王红玲;

【Author】 HONG Yan, LIU Yu ming, XIONG Xiao hong,et al (Department of Pediatrics, The Zhongnan Hospital of Wuhan University, Wuhan 430071, China)

【机构】 武汉大学中南医院; 武汉大学中南医院 湖北武汉430071; 湖北武汉430071; 湖北武汉430071;

【摘要】 目的进一步了解当归多糖的药用价值。方法将小鼠分为正常对照组 ,照射对照组 ,当归多糖治疗组 ,检测三组的红细胞C3b受体花环率和外周血象。结果照射对照组红细胞C3b受体花环率和外周血白细胞、血小板明显低于正常对照组 ,而当归多糖治疗组的红细胞C3b受体花环率和外周血白细胞、血小板显著高于照射对照组 ,有统计学意义 (P <0 .0 1)。结论当归多糖对放射损伤小鼠红细胞免疫功能和造血功能具有保护作用

【Abstract】 ObjectiveTo understand further the pharmaceutical importance of Angelica polysaccharide (AP).MethodsThe mice were divided randomly into three groups: normal group, radiated control group and AP treated group. Their erythrocyte C3b receptor garland rate and peripheral blood picture were examined.ResultsErythrocyte C3b receptor garland rate , WBC and PLT counts in peripheral blood of the radiated control group were obviously lower than those of the normal group; whereas those of the AP treated group were significantly higher than the results of radiated control group (P<0.01).ConclusionAP displays protective effects on the function of erythrocyte immunity and hematopoiesis in mice damaged by radiation.

  • 【文献出处】 医学临床研究 ,Hunan Medical Journal , 编辑部邮箱 ,2002年03期
  • 【分类号】R285.5
  • 【被引频次】108
  • 【下载频次】342
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