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肝硬化患者血清总胆汁酸水平与Child-Pugh分级的关系

Relationship between serum total bile acid levels and Child-Pugh classification in patients with liver cirrhosis

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【作者】 杜红缨

【Author】 DU Hong ying.(The First People’s Hospital of Zhaoqing city,Guangdong 526021,China)

【机构】 广东省肇庆市第一人民医院消化内科 526021

【摘要】 目的 探讨肝硬化患者血清总胆汁酸 (TBA)与肝功能 Child- Pugh分级的关系。方法 检测肝硬化患者 6 6例及正常对照组 2 2例的血清总胆汁酸。结果 肝硬化组 TBA(49.6± 4 7.8)μmol/L明显高于对照组 (6 .4± 2 .5 ) μmol/L,P<0 .0 1;且在肝功能 Child- Pugh分级中 ,具有 C级 >B级 >A级的规律。结论 TBA对判断肝硬化患者肝功能状态、Child- Pugh分级有一定参考价值

【Abstract】 Objective To study the relationship between serum total bile acid(TBA) levels and Child Pugh classification in patients with liver cirrhosis.Methods The levels of TBA were measured in 66 patients with cirrhosia and 22 normal controls.Results The levels of TBA were significantly higher in patients with cirrhosis(49.6±47.8 μmol/L)than in controls(6.4±2.5 μmol/L), P <0.01.Comparisons of the levels of TBA in group of patients with different liver function were shown as follows:Child Pugh C>Child Pugh B>Child Pugh A.Conclusion The level of TBA is closely associated with the severity of liver cirrhosis and TBA is suitable for objective analysis of Child Pugh classification.

  • 【文献出处】 淮海医药 ,Journal of Huaihai Medicine , 编辑部邮箱 ,2002年06期
  • 【分类号】R575.2
  • 【被引频次】4
  • 【下载频次】26
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