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固定化米曲霉菌体填充床拆分DL-丙氨酸的动力学行为

Kinetics of Mycelium-immobilized Packed Bed Continuous Resolution of DL-alanine

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【作者】 王燕张凤宝宋正孝张国亮王诤赵林

【Author】 WANG Yan, ZHANG Feng-bao, SONG Zheng-xiao, ZHANG Guo-liang, WANG Zheng, ZHAO Lin (School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China)

【机构】 天津大学化工学院天津大学化工学院 天津300072天津300072天津300072

【摘要】 分析了固定化米曲霉拆分DL-丙氨酸的动力学特性,通过间歇反应器的实验数据处理,获得了酶促反应的动力学参数. 应用填充床的一维稳态轴向扩散模型进行数值求解,得到了模型计算值,与实验结果比较表明,提出的模型能较好地描述固定化菌体连续拆分DL-丙氨酸过程.

【Abstract】 Based on the systematical study of continuous resolution of DL-alanine employing the immobilized Aspergillus oryzae cell, the kinetics of the enzymic reaction was determined. Furthermore, the method of Newton-Raphson was applied to the solution of one-dimension-steady-diffusion model of packed bed for continuous resolution of DL-alanine. The calculated results of the model, with the error less than 10%, were in good agreement with those of experiments. It was demonstrated that the model was reasonable and accurate.

  • 【文献出处】 过程工程学报 ,The Chinese Journal of Process Engineering , 编辑部邮箱 ,2002年02期
  • 【分类号】TQ223
  • 【被引频次】10
  • 【下载频次】78
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