【摘要】 在近临界水中进行有机合成为可持续化学合成提供了新的途径。对近临界水中苯甲醛与丙酮的Claisen-Schmidt缩合反应的研究表明,在没有外加任何催化剂的条件下,苯甲醛与丙酮可顺利地发生缩合反应,近临界水在其中兼作溶剂和催化剂,避免了碱催化剂的使用和随后繁杂的中和、分离步骤以及产生废弃盐等弊端。温度、反应时间和初始水量对反应的转化率和苯丁烯酮的产率有不同的影响。更多还原

【Abstract】 To perform organic synthesis in near-critical water offers a new opportunity for the development of sustainable chemical synthetic process. Investigation of Claisen-Schmidt condensation reaction using near-critical water as media indicated that the reaction can be carried out in near-critical water without any added catalyst. Since near-critical water acts as both solvent and catalyst, the subsequent need for neutralization and salt disposal in the classical method were avoided. The conversion of benzaldehyde and yield of benzylidene acetone were influenced by reaction time, temperature and initial water volume.更多还原