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聚羟乙谷胺酰胺的制备及生物降解性能研究

Study on Preparation and Biodegradability of Poly Hydroethyl Glutamine

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【Author】 Zhang Jingxia Pan Shirong Wang Qingmei Pan Aihua( Dept. of Chemistry, Medical School, Zhongshan University, Guangzhou 510089; (Artifictal Heart Lab , The First Affiliated Hospital, Zhongshan University, Guangzhou 510089)

【机构】中山大学中山医学院化学教研室；中山大学附属第一医院人工心研究室；中山大学附属第一医院人工心研究室广东广州； 510089；广东广州；广东广州； 510089；

【摘要】通过聚谷氨酸苄酯（PBLG）和2-氨基乙反应制备聚羟乙谷氨酰胺（PHEG）;通过羟基含量测定、酶解反应和凝胶色谱法研究了它的水溶性和生物降解性能;实验结果表明:该聚合物具有很好的水溶性和良好的生物降解性能。更多还原

【Abstract】 Abstract Poly hydroethyl glutamine(PHEG) was prepared first by the reaction of poly (7 - benzyl - L-glutarnate) (PBLG) with 2- aminoethanol; then water- solublility was studied by detecting the content of hy-droxyl of PHEG , and biodegradablility was studied by enzmolysis reaction and gel permeation chromatography (GPC). The results show that the compound has excellent water-solubility and biodegradability.更多还原

【关键词】聚羟乙谷氨酰胺；生物降解性能；酶解反应；凝胶色谱；
【Key words】 Poly hydroethyl glutamine biodegradablility enzmolysis GPC；

【文献出处】广州化工 ,Guang Zhou Chemical Industry and Technology , 编辑部邮箱 ,2002年02期

【分类号】TQ323
【下载频次】77

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