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蒙特卡罗模拟激光诱导间质热疗中激光能量在肿瘤组织内的传播
MONTE-CARLO SIMULATION OF LASER ENERGY DISTRIBU TION IN THE TUMOR TISSUE DURING LASER-INDUCED INTERSTITIAL THERMOTHERAPY (LITT)
【摘要】 激光诱导间质热疗手术方案的制定需要术前对引入激光能量在组织中的分布进行准确的数值模拟。考虑肿瘤大小、光学特性与周围正常组织的差别,建立激光诱导间质热疗时的肿瘤与正常组织两层结构模型,采用蒙特卡罗方法模拟激光在其中的传播,得到激光能量在组织中的分布规律,并采用Pennes生物传热方程计算得出组织的稳态温度分布,这对于激光诱导间质热疗的临床应用具有积极的理论指导意义。
【Abstract】 The operation of LITT needs an accurate numerical simulation of laser energy distribution ?? the tissue. Considering the size, the optical property of tumors and their difference from surrounding normal tissue, a two-layer tissue configuration model for LITT is set up, and then energy distribution in the configuration is simulated with Monte Carlo method. On the basis of energy distribution, the steady-state temperature distribution is computed with Pennes equation. All of these will provide an important theoretical guide for clinic application of LITT.
【Key words】 Monte-Carlo simulation; LITT; photon distribution; bioheat transfer;
- 【文献出处】 工程热物理学报 ,Journal of Engineering Thermophysics , 编辑部邮箱 ,2002年S1期
- 【分类号】R730.57
- 【被引频次】2
- 【下载频次】162