【摘要】 目的　探讨新的凋亡相关基因TFAR19在系统性红斑狼疮 (SLE)发病机制中的作用 ,及其与SLE病情的关系。方法　利用酶联免疫吸附分析 (ELISA)方法检测TFAR19与SLE患者病情的关系。结果　发现活动期SLE患者血清中TFAR19的抗体值高于稳定期和正常对照组 (P≤0 0 5 )。结论　TFAR19可能和SLE的发病和病情有关更多还原

【Abstract】 Objective To explore the role of a new apoptosis related gene TFAR 19 in the pathogenesis of systemic lupus erythematosus (SLE) and the relationship between TFAR 19 and SLE.Methods ELISA was used to test if there is relation between TFAR 19 and SLE.Results It was found that in active SLE patients there was higher titer of TFAR 19 antibody than that in stability patients and normal controls.No significant difference was seen between stability patients and normal controls.Conclusion It is first put forward that TFAR 19 may be related with SLE pathogenesis and disease activity.更多还原