【摘要】 端粒是存在于线性染色体末端的一段特殊的 DNA-蛋白质复合物 ,由于末端不能复制 ,正常体细胞随着细胞分裂的进行而逐渐丢失端粒序列 ,导致细胞老化和死亡。端粒酶是维持端粒长度的一种特殊的 DNA聚合酶 ,在细胞的增殖、衰老及永生中起重要作用。本文就端粒和端粒酶及其与衰老的关系作一综述更多还原

【Abstract】 Telomere is a kind of compound of a part of special DNA and protein in linear chromosome’s end. Because the end doesn’t copy and the normal somatic cells gradually loss telomeres sequence with cell division, so it results in senescence and death of cells. Telomerase is a kind of special DNA polymerase maintaining telomeres length and play an important role in proliferation, senescence and eternal life of cells. This paper summarized the relation between telomere, telomerase and aging.更多还原