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Th-GSH单层膜修饰电极和多巴胺的准可逆响应

Thionine-glutathione Self-assembly Monolayer Modified Electrdoe and the Quasi-reversible Response of Dopamine

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【作者】 方程栾政张悟铭周性尧

【Author】 FANG Cheng, LUAN Zheng, ZHANG Wu_Ming,ZHOU Xing_Yao * (Department of Chemistry, Wuhan University, Wuhan 430072,China)

【机构】 武汉大学化学系武汉大学化学系 湖北武汉430072湖北武汉430072湖北武汉430072

【摘要】 在谷胱甘肽 (GSH)自组装膜 (SAM )修饰的金电极表面共价固定硫堇 (Th)分子 ,研究其电化学性质及相关应用 ,发现该电极对多巴胺 (DO)有准可逆响应 .利用多巴胺的还原峰可在较高浓度的抗环血酸 (AA)存在条件下 (10 0倍 )对多巴胺进行检测 ,线性响应范围为 1.0~ 30 0 μmol·L- 1.

【Abstract】 Thionine was bound onto a glutathione monolayer self_assembled on the surface of a gold electrode previously, the electrochemical characteristics of which were studied. It was found that dopamine had a quasi_reversible response and cathodic characterstics peak could be used to determine the concentration of dopamine in the range of 1.0~300 μmol·L -1 in the presence of a higher concentration of ascorbic acid.

【关键词】 谷胱甘肽硫堇多巴胺抗环血酸自组装膜
【Key words】 GlutathioneThionineDopamineAscorbic acidMonolayer
  • 【分类号】O657.1
  • 【被引频次】5
  • 【下载频次】77
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