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潘托拉唑钠治疗溃疡合并上消化道出血的疗效观察
Effect of Pantoprazole in the Treatment of Peptic Ucler Bleeding
【摘要】 目的:评价潘托拉唑在治疗溃疡合并上消化道出血中的疗效。方法:57例经病史、临床检查及胃镜检查证实为消化性溃疡合并出血的病人随机分为两组,治疗组中潘托拉唑用量为每天40一80mg静脉滴注,对照组中雷尼替丁用量为每天300-400mg静脉滴注。结果:治疗组总有效率为96.9%(31/32),其中显效占90.6%(29/32),有效占6.3%(2/32)无,效为3.1%(1/32)。对照组中总有效率为84.0%(21/25),其中显效占36.0%(9/25),有效占48.0(12/25),无效占16.0%(4/25)。统计结果显示,治疗组疗效明显优于对照组(P<0.01)。结论:潘托拉唑治疗溃疡合并消化道出血疗效满意。
【Abstract】 Objective: To evaluate the effect of pantoprazole in the treatment of ulcer bleeding. Methods; Fifty-seven patients with ulcer bleeding were randomly divided into two groups. Pantoprazole was used in a dose of 40-80mg intravenous injection daily in the treated group and ranitidine 300-400mg intravenous injection daily in the control group. Results: The total effective rate of the treated group was 96.9%(31/32), 90.6(29/32) markedly effectively, 6.3%(2/32)effectively and 3.1%(1/32)ineffectively, while in the control group they were 84.0% (21/25), 36.0%(9/ 25), 48.0%(12/25) and 16.0%(4/25). The effect of the treated group was better than that of the control group, the difference between these two groups was significant(P<0.01). Conclusion; Our data showed that the effect of PT in treatment of ulcer bleeding was satisfactory.
【Key words】 pantoprazsole; peptic ulcer; upper gastrointestinal bleeding;
- 【文献出处】 当代医学 ,China Comtemporary Medicine , 编辑部邮箱 ,2002年01期
- 【分类号】R573.1
- 【被引频次】1
- 【下载频次】11