【摘要】 用人用疫苗强化免疫奶水牛或奶牛来生产免疫乳 ,乳汁中甲肝抗体的相对活性效价峰值维持了 1周 ,相对活性效价值在 1.7左右 ,甲抗的相对活性效价在完成全程免疫后除峰值期外 ,都基本维持在一个较低的水平 ,相对活性效价大都在 1.2～ 1.5之间变动。霍乱孤菌抗体、伤寒杆菌抗体、痢疾杆菌抗体在乳汁中出现的时间要比甲抗出现的时间迟 ,且维持的时间很短 ,霍乱孤菌抗体和伤寒杆菌抗体在乳汗中能维持 5周左右 ,痢疾杆菌抗体在乳汁中只维持一个星期。更多还原

【Abstract】 kinds of human medical vaccines (to hepatitis A, cholera, dysentery and typhoid fever, respectively )were used to intensively immunize the Holland cows and milk buffalo. The phases of relevant anti-bodies in the milk appeared after immunization were observed and some of the deference between the immune milk from Holland cows or buffalo was compared. Technological process of drawing the immune substances from the immune milk was investigated, and the bacteriostasis effects of the immune substances from the immune milk were defined. Results showed: (1) Antibodies to hepatitis A could be detected from blood of Holland cows as well as buffalo one week after immunization and it could be detected from milks produced by the two kind of animal after immunization. The activity peaking of antibodies in the buffalo milk could be seen in the 18th week (9 weeks after immunization), one week later than that in cow milk. The peaking activity values of both milks could maintain for about one week. Antibodies to vibrio cholerae, to bacilli of typhoid fever or dysentery, appeared one or two weeks after immunization, with relatively low activity value. Among them, the activity of antibodies to vibrio cholerae and to bacillus of typhoid fever could last for 5 weeks, while that of antibodies to bacillus of dysentery could last for week only.更多还原