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不同型号白油ND油乳剂灭活苗免疫比较实验

Comparison of the Immune Effect of Different mineral Oil-Adjuvant ND Vaccines

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【作者】 徐怀英秦卓明何叶峰欧阳文军王传强金维江

【Author】 XU Huai-ying,QIN Zhuo-ming,HE Ye-feng,OU YANG Wen-jun,WANG Chuan-qi ang,JIN Wei-jiang(Institute of Poultry Sciences,SAAS,Jinan250100)

【机构】 山东省家禽研究所SPF鸡研究中心山东省家禽研究所SPF鸡研究中心 济南250100济南250100济南250100

【摘要】 用7#白油及兽用白油分别与乳化剂和ND尿囊液制备油乳剂灭活疫苗,疫苗检验合格后,免疫8周龄SPF鸡。免疫后每周检测血清中ND抗体滴度,并观察油苗的吸收情况。试验结果表明,与7#白油疫苗相比,兽用白油疫苗粘稠度稍低,但吸收速度快、抗体上升水平高,免疫效果较好。

【Abstract】 ND oil-emulsions were separetly prepared by using two kinds of oils (7#Oil and Animal-Mineral Oil).SPF chicks were inoculated with the two i nactived vaccines,and titers of ND-HI antibody and absorbtion of vaccine were detected every week.The experiment results showed that comparing with7#Oil ,Aimal-Mineral Oil has lower viscosity,more quickly ab-sorbtion speed and hi gher titers of ND-HI antibody level.Generally speaking Animal-Mineral Oil wa s better as immune adjuvant .

【关键词】 佐剂疫苗免疫效果
【Key words】 AdjuvantVaccineImmune Effect
  • 【分类号】S859.797
  • 【被引频次】7
  • 【下载频次】192
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