【摘要】 目的　研究短暂性脑缺血发作 (TIA)患者血浆纤溶功能的变化。方法　对 2 2例颈内动脉系统TIA患者血浆组织型纤溶酶原激活物 (t PA)及其快速抑制物 (PAI)的活性、D 二聚体 (D D)及纤维蛋白原 (FbG)含量进行检测 ,并与对照组进行比较。结果　TIA组血浆t PA活性明显低于对照组 (P <0 .0 5 ) ,而PAI活性和D D及FbG含量则明显高于对照组 (P <0 .0 5 )。结论　TIA患者存在血浆纤溶功能异常 ,可能为TIA反复发作的一个重要因素更多还原

【Abstract】 Objective To study the alteration of plasma fibrinolytic function in patients with transient ischemic attack(TIA).Methods Activities of tissue type plasminogen activator(t PA) and plasminogen activator inhibitor(PAI) and contents of D dimeter(D D) and fibrinogen(FbG) were determined in 22 patients with TIA and compared with 22 normal controls.Results Plasma t PA activity level in TIA group was significantly lower than that in control group ( P <0.05).But the levels of PAI,D D and FbG in TIA group were significantly higher than those in control group ( P <0.05). Conclusions Abnormal fibrinolytic function may be an important factor of TIA recurrence in TIA patients.更多还原