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聚焦超声手术目标定位中的呼吸幅度测量

Respiratory Amplitude Measurement in Target Localization for Focused Ultrasound Surgery

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【作者】 高爽陈亚珠高巍

【Author】 GAO Shuang\+1, CHEN Yazhu\+1, GAO Wei\+2. 1 Dept. of Biomedical Eng., Shanghai Jiaotong University, Shanghai\ 200030; 2 Physics Team, No.9 Middle School, Jilin Chemical Industrial Group Corp.,Jilin\ 132022

【机构】 上海交通大学生物医学工程系吉化公司第九中学物理组 上海200030上海200030吉林132022

【摘要】 聚焦超声手术是一种非常有前途的微损伤手术技术。目标定位是决定手术成功与否的重要方面。在平静状态时 ,呼吸运动是影响手术目标定位的主要因素。为了分析呼吸幅度与目标运动之间的关系 ,研制了一套呼吸幅度测量系统。该系统主要包括呼吸幅度传感器、信号调理与放大电路、数据采集卡以及计算机等组成。该系统通过测量人体胸廓周径随呼吸运动的变化来获得呼吸幅度。同时 ,为了检验所研制系统的可行性 ,另外设计了一套系统 ,该系统通过医学超声图像计算膈随呼吸运动的位置变化来获得呼吸幅度。两套系统对处于平静呼吸状态的受试者进行了同步数据采集 ,经过对两套数据预处理并做互相关运算 ,得到互相关系数为0 976 5 ;同时计算得到膈的最大运动范围为 13 88mm ,在正常范围内。上述结果表明了所研制的呼吸幅度测量系统是可行的

【Abstract】 Focused Ultrasound Surgery (FUS) is a promising minimally invasive surgery technique. Target localization is one of the most important aspects that determine if FUS will be successful or not. Respiration movement is the primary factor affecting target localization while the patient is in a quiet state. In order to analyze the relationship between respiratory amplitude and target motion, a respiratory amplitude measurement system was developed. This system acquires respiratory amplitude data by measuring the variation of circumference of thorax during breathing. This system mainly consists of respiratory amplitude transducer, signal conditioning and amplifying circuits, data acquisition board and computer. For the sake of verifying the feasibility of the developed system, another system, which acquires respiratory amplitude data by calculating the variation of position of diaphragm in medical ultrasonic images during breathing, was also designed. These two systems were used to acquire synchronously respiratory amplitude data while the subjects were in quiet breathing state. After the two sets of data were preprocessed, the cross\|correlation processing was done and the cross\|correlation coefficient was 0\^9765. Meanwhile, the calculated maximum movement of the diaphragm was 13\^88mm, which was in the normal range. The above mentioned results indicate that the developed respiratory measurement system is feasible.

【基金】 上海市科技发展基金项目 ;项目编号 9944 190 2 7。
  • 【文献出处】 北京生物医学工程 ,Beijing Biomedical Engineering , 编辑部邮箱 ,2002年02期
  • 【分类号】R311
  • 【下载频次】46
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