【摘要】 对Graves′病患者 ,用放射免疫分析法 (RIA)测定了IL -6和TNF -α,用双抗体夹心ELISA法测定了IFN -γ。Graves′病患者的IL -6、TNF -α、IFN -γ水平均高于对照者。治疗后 ,IL -6水平降至正常 ,而TNF-α、IFN -γ水平仍高于对照者。提示 :IL -6水平与病情变化相平行 ,而TNF -α、IFN -γ水平仍较高。更多还原

【Abstract】 Serum concentrations of IL-6, TNF-α, IFN-γ in GD patients were measured before and after treatment by RIA and double-antibodies ELISA, respectively. The results showed that IL-6, TNF-α, IFN-γ levels in GD patients were significantly higher than those in control subjects ( P <0.01). After treatment, IL-6 level returned to normal level, TNF-α,IFN-γ levels were still higher. It showed that IL-6 level was paralleled with disease′s state; the changes of TNF-α, IFN-γ levels reflected the remission of immutal treatment.更多还原