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低分子肝素联合阿司匹林治疗梗死后心绞痛

Low-molecular heparin in combination with aspirin for treatment of postinfarction angina pectoris

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【作者】 张宁汝

【Author】 ZHANG Ning ru (Department of Cardiovascular Diseases,Affiliated Hospital of Bengbu Medical College,Anhui 233004 ,China)

【机构】 蚌埠医学院附属医院心血管科 安徽蚌埠233004

【摘要】 目的 :探讨低分子肝素联合小剂量阿司匹林治疗梗死后心绞痛的疗效。方法 :采用随机分组 ,将 4 0例梗死后心绞痛患者分为两组。治疗组 :低分子肝素 0 .3ml,皮下注射 1次 /天 ,连用 7天 ,加服阿司匹林 15 0mg/d。对照组 :口服阿司匹林15 0mg/d。观察治疗前后、梗死后心绞痛发作频率及发作持续时间的变化 ,并进行统计学分析。结果 :低分子肝素联合小剂量阿司匹林治疗后心绞痛发作频率减少 ,发作持续时间缩短 ,与对照组差异均有显著性 (P <0 .0 0 1)。且无明显并发症。结论 :低分子肝素联合小剂量阿司匹林治疗梗死后心绞痛疗效显著

【Abstract】 Objective:To examine the efficacy of low molecular in combination with aspirin in treatment of postinfarction angina pectoris.Methods:Forty postinfarction angina pectoris patients were randomly divided in two groups.Cure group:low molecular heparin 0.3 ml/d injected subcutaneously for seven days plus aspirin 150 mg/d.Control group:Aspirin 150 mg/d was administered and the paroxysmal frequency,paroxysmal panes and side effects were observed before and after the drug therapy.Results:The frequency and duration of angina pectoris attacks in the cure group decreased significantly compared with those in the control group( P <0.001).And few side effects were found.Conclusions:Low molecular heparin in combination with aspirin are more effective than aspirin alone in the treatment of postinfarction angina pectoris.

  • 【文献出处】 蚌埠医学院学报 ,Journal of Bengbu Medicinae College , 编辑部邮箱 ,2002年04期
  • 【分类号】R541.4
  • 【被引频次】1
  • 【下载频次】18
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