【摘要】 目的　探讨原发性肾病综合征 (PNS)患者D 二聚体变化及临床意义。方法　用免疫浊度法测定 45例PNS患者和 30例正常人血浆D 二聚体含量。结果　PNS患者D 二聚体显著高于正常对照组 (P <0 0 1) ,其中肾功能不全者D 二聚体显著高于肾功能正常者。结论　PNS患者存在抗凝作用减弱、纤溶活性增高 ,在合并肾功能不全患者中尤为明显。更多还原

【Abstract】 AIM To investigate the variation and the clinical significance of the serum D-Dimer in primary nephrotic syndrome (PNS). METHOD Immunologic titer method was used to examine the content of the serum D-Dimer in 45 PNS patients and 30 normal controls.RESULTS The PNS D-Dimer in 45 cases were prominient higher than the 30 controls (P<^01).In the patients of PNS combined with renal failure,D-Dimer was significantly higher than the formers with normal renal function.CONCLUSION The role of the anticoagulation in PNS cases was decreased and the fibrinolysis was increased,especially is the one coplicated with renal failure.=更多还原