【摘要】 目的 :评估大肠癌 (LBC)患者及其家族成员 (FM)血清免疫抑制酸性蛋白 (IAP)水平的变化。方法 :应用单向免疫琼脂扩散法检测 2 0例大肠癌患者和 2 0例家族成员血清IAP水平。结果 :2 0例LBC患者血清IAP水平与正常健康人比较有显著差异 (P<0 .0 1) ,FM组与正常健康人 (NS)比较也有统计学差异 (P <0 .0 1)。结论 :IAP与大肠癌发生可能相关 ,IAP的检测可被用于大肠癌易感个体的筛选。更多还原

【Abstract】 Purpose: to evaluate the changes af the serum levels of immunosuppressive acidic protein (IAP) in patients with large bowel carcinoma(LBC) and their familial members (FM). Methods: the serum changes of IAP in the 20 cases with LBC and 20 FM were determined using single immunodiffusion method. Results: the serum levels of IAP in patients with LBC, compared with normal subjects (NS), were significantly increased {(P<0.01)}. there also were statistical differences in serum levels between FM and the NS (P<0.01). conclusion: It is suggested that IAP may probably be associated with carcinogenesis of LBC. The changes of IAP may be served as an indicator of diagnosis for susceptible individuals of LBC.更多还原