【摘要】 目的 :观察音乐疗法在肿瘤临床治疗中的作用。方法 :采用音乐疗法 (辨证施乐 )配合抗肿瘤治疗 (化疗和中药辨证论治 ) ,观察了 16 2例肿瘤患者的抑郁自评量表 (SDS)、焦虑自评量表 (SAS)、明尼苏达多相个性测定 (MMPI)、汉密顿抑郁量表 (HAMD)及T淋巴细胞亚群 (免疫组化法 )、自然杀伤 (NK)细胞抗肿瘤活性测定 (NAG法 )等指标的变化。结果 :治疗后SDS、SAS的分值治疗组明显低于对照组 ,差异有显著性 (P <0 0 5 ,P <0 0 1)。MMPI治疗组中诈病 (F)、疑病 (HS)、抑郁 (D)、精神衰弱 (Pt)的分值 ,较治疗前差异有显著性 (P <0 0 1,P <0 0 5 ) ;对照组中唯HS差异有显著性 (P <0 0 5 )。HAMD治疗组睡眠困难、早醒、工作和兴趣、全身症状、疑病等症状均有改善 (P <0 0 5 ) ,忧郁情绪、入睡困难、精神性焦虑、躯体性焦虑等有显著改善 (P <0 0 1) ;对照组中只有工作和兴趣、疑病有所改善 (P <0 0 5 )。T淋巴细胞亚群两组治疗后CD8均有所下降 (P <0 0 1) ,但治疗组治疗后CD3 、CD4 、CD4 /CD8比值无明显变化 (P >0 0 5 ) ,对照组治疗后CD3 、CD4 、CD4 /CD8比值下降较明显 (P <0 0 5 )。NK细胞抗肿瘤活性治疗组治疗前后无明显差异 (P>0 0 5 ) ;对照组治疗前后差异有显著性 (P <0 0 5 )。结论 :音乐疗?更多还原

【Abstract】 Objective: To observe the clinical effect of music therapy in treating tumor patients. Methods: Music therapy combined with anti tumor drugs, including chemotherapy and Chinese drugs, was given to 162 tumor patients according to syndrome differentiation to observe the change of self rating depression scale (SDS), self rating anxiety scale (SAS), minnesota multiphasic personality inventory (MMPI), Hamilton rating scale for depression (HAMD) and T lymphocyte subsets (immuno histochemical assay), NK cell anti tumor activity (NAG method), etc. while 46 caces didn′t receive music therapy were taken as the control group. Results: The scale marks of SDS and SAS of the treated group after treatment were obviously lower than that of the control group significantly (P<0 05, P<0 01). After treatment, the average values of MMPI on falseness (F), hypochondriasis (HS), depression (D) and psychosthenia (Pt) in the treated group were all improved (P<0 01 or P<0 05); but in the control group, significant difference only showed in MMPI on HS (P<0 05). HAMD in the treated group revealed some improvement in insomnia, early awakening, daily work and interest, systemic symptoms and hypochondriasis (P<0 05), and significant improvement in depression, difficulty in falling asleep, psychiatric anxiety and somatic anxiety (P<0 01); while in the control group, only work interest and HS had some improvement (P<0 05). CD 8 percent was reduced in both groups after treatment (P<0 01), but in the treated group CD 3, CD 4 and CD 4/CD 8 ratio were not significantly changed after treatment (P>0 05); while in the control group they lowered obviously (P<0 05). As for NK cell anti tumor activity in the treated group before and after treatment, it was not significantly lowered (P>0 05); while in the control group the lowering after treatment was significant (P<0 05). Conclusion: Music therapy could regulate the emotion of tumor patient, optimize the emotional effect, improve the somatic symptoms, enhance the immune function, motivate the active principle and raise the self regulating power in the body.更多还原