Objective: To investigate the protective effect of Congsheng capsule (CSC) on acute cerebral ischemia in mice and rats. Methods: Cerebral ischemia model was established by adding FeCl 3 to block the blood flow of unilateral middle cerebral artery (MCA) for 30 mins. Acute incomplete cerebral ischemia was induced by ligation of bilateral carotid arteries in rats. Bilateral carotid arteries of old mice were repeatedly ischemia and reperfusion combined with caudal bloodletting to build the cerebral ischemia mo...