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黄芪增免散对围手术期食管癌间质反应的影响

Effect of Huangqi Zengmian Powder on Interstitial Response in Patients with Esophageal Cancer at Peri-Operational Period

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【作者】 高新平; 赵卫星; 张志亮; 刘彩莉; 李汉臣; 杜华贞; 杨廷桐;

【Author】 GAO Xin ping, ZHAO Wei xing, ZHANG Zhi liang, et al Department of Pathology, Xinxiang Medical College, Henan (453003)

【机构】 新乡医学院病理学教研室!(河南453003); 新乡医学院第一附属医院;

【摘要】 目的 :观察黄芪增免散对围手术期食管癌间质反应的影响。方法 :用黄芪增免散治疗围手术期食管癌患者 37例 ,共 4周。采用甲苯胺蓝染色方法 ,对手术切除标本进行组织学观察用药后食管癌间质(包括肥大细胞、微血管和淋巴细胞 )反应的变化 ,并与同期手术治疗的 14例患者作对照。结果 :与对照组比较 ,治疗组食管癌间质肥大细胞数量和淋巴细胞灶状聚集增多 ,间质微血管损伤现象明显 (P <0 0 1)。结论 :黄芪增免散对围手术期食管癌患者免疫功能有改善作用。

【Abstract】 Objective: To observe the effect of Huangqi Zengmian Powder (HQZMP) on interstitial response of esophageal cancer at peri operational period. Methods: Thirty seven patients of esophageal cancer were treated with HQZMP for 4 weeks peri operationally. The pathological interstitial changes (including mastocyte, microvessels and lymphocytic response) in resected esophageal cancer sample were observed using toluidine blue stain. Results: As compared with the non HQZMP treated control group, quantity of interstitial mastocyte, focal lymphocytic aggregation and interstitial microvessel damage in the HQZMP treated group were more obvious (P<0 01). Conclusion: HQZMP could improve the immune function of esophageal patients in peri operational period.

【基金】 河南省教委科研基金
  • 【文献出处】 中国中西医结合杂志 ,Chinese Journal of Integrated Traditional and Western Medicine , 编辑部邮箱 ,2001年03期
  • 【分类号】R735.1
  • 【被引频次】24
  • 【下载频次】60
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