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热休克蛋白27表达与卵巢癌预后

THE RELATIONSHIP BETWEEN THE EXPRESSION OF HSP27 AND THE PROGNOSIS OF OVARIAN CARCINOMA

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【作者】 李琳陈惠祯张广平

【Author】 LI Lin, CHEN Hui-zhen, ZHA NG Guang-ping, Department of Gynecology,the Centre Hospital,Xianfan 441021, Ch ina

【机构】 湖北襄樊市中心医院妇产科!襄樊441021湖北医科大学附属第二医院肿瘤科

【摘要】 目的 探讨热休克蛋白 2 7表达卵巢癌预后的关系。方法 用免疫组化S P法检测了 45例卵巢癌组织中HSP2 7的表达情况。结果 HSP2 7表达阳性率为 6 2 2 2 % ,HSP2 7表达与患者年龄、肿瘤的组织类型、组织分级和残留大小无关 ,与临床分期和术后生存期都相关。结论 HSP2 7表达能作为预测卵巢癌预后的因素之一

【Abstract】 Objective To investigate the relationship between heat shoc k protein 27 (HSP27) expression and the prognosis of ovarian carcinoma.Met hods The S-P immunohistochemical method was used to study HSP27 expres sion in 45 cases of ovarian carcinoma. Results HSP27 positive expression rate was 62 22 %. The expression had no correlation w ith the age of patients, histologic type, histologic grade and residual tumor, b ut it was significantly related to the clinical stage and post-operative surviv al time. Conclusion Expression of HSP27 may be one of the progn ostic factors of ovain carcinoma

  • 【分类号】R737.31
  • 【被引频次】15
  • 【下载频次】80
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