【摘要】 目的 :分析母体血清妊娠相关血浆蛋白A(PAPP -A)水平与异常妊娠的联系 ,探讨PAPP -A浓度是否可用于产前筛查胎儿染色体异常。方法 :96 0例孕妇血清PAPP -A浓度用酶联免疫吸附法测定。选择胎儿染色体异常作回顾件分析异常妊娠结局的发生率与PAPP -A浓度的关系。结果 :低浓度的PAPP -A与胎儿染色体异常有联系。结论 :母体血清PAPP -A浓度可用来筛查胎儿染色体异常。更多还原

【Abstract】 Objective:To probe into the relationship between the level of PAPP-A and fetal chromosomal anomaly.Methods:blood samples from 960 pregnant women were assayed for PAPP-A by enzyme-linked immunosorbent assay procedures.The incidences of fetal chromosomal anomaly and selected adverse pregnancy outcomes were correlated to PAPP-A concentration.Results:In 3 cases of chromosomal anomaly,levels of PAPP-A were <0.75MOM,with a range of 0.12-0.73MOM.Low level of PAPP-A was also associated with fetal chromosomal anomaly.Conclusion:Maternal serum PAPP-A might be a marker for predicting fetal chromosomal anomaly.更多还原