节点文献
大黄滴眼剂的研制
Study on the pharmaceutics of Redix et Rhizoma Rhei eye drops
【摘要】 目的:研制中药滴眼剂,治疗结膜炎。方法:采用反相高效液相色谱法。进行稳定性考察及药理学研究。结果:回收率98.32%~102.9%,3.03%<RSD<4.33%,体外对金葡菌MIC 1/10,大肠杆菌MIC 1/5。结论:大黄滴眼剂制备工艺及质量可靠,有体外抑菌作用,可试用于临床。
【Abstract】 Objectives: To develop a kind of eye drops with a Chinese herb. It can be used to treat conjunctivitis. Method: Stability test and pharmacological experiment by HPLC. Result: The recovery was 98.32 %-102.9 %. RSD ranged from 3.03 % to4.33%. The MIC to Staphylococcus aureus was 1 /10 and MIC to Excherichia coli was 1 /5 in vitro. Conclusion: The method is feasible, the quality of Redix et Rhiznma Rhei eye drops is dependable. The action of inhibiting bacteria is obvious in vitro. It can be tried to be used in clinics.
【关键词】 大黄;
滴眼剂;
含量/测定;
试验,稳定性;
【Key words】 Redix et Rhizoma Rhei; Eye drops; Content determination; Stability test;
【Key words】 Redix et Rhizoma Rhei; Eye drops; Content determination; Stability test;
- 【文献出处】 中国药师 ,China Pharmacist , 编辑部邮箱 ,2001年02期
- 【分类号】R943
- 【被引频次】5
- 【下载频次】115