【摘要】 [目的]为探讨微量元素硒(Se)和锰(Mn)与肾病综合征(NS)发病的关系。[方法]采用原子吸收分光光度仪,对36例急性期小儿肾病综合征及24例健康儿进行微量元素硒和锰检测。[结果]肾病组患儿Se和Mn含量显著低于正常对照组(t=3.51,P<0.01;t=2.43,P<0.05)。血清Se和Mn与血清白蛋白、24小时尿蛋白之间具有相关性。[结论]Se和Mn含量减少,表明NS急性期存在着抗氧化能力下降,亦可能是容易感染和复发的原因之一。更多还原

【Abstract】 [Purpose] To find the relationship between nephrotic syndrome (NS) and trace element - Se and Mn. [Method]The content of Se and Mn were separately measured, with atomic absorption spectrometry (AAS), for 36 children with acute NS and 24 healthy children. [Result]The content of Se and Mn of children in nephrosis group were significantly lower then that of normal contrast group (t = 3.51 ,p< 0.01 ;t = 2.43,p< 0.05). The content of Se and Mn in serum was related to white protein and urinary protein of 24 hours. [Conclusion]The reduction of Se and Mn content indicate a drop of antioxidation in NS acute stage. It may be one of the causes of an easy infection and recurrence with NS.更多还原