【摘要】 目的:探讨菊花解热、降压作用的物质基础。方法:采用大鼠肛温表测定体温、大鼠颈动脉插管法测定血压值。结果:菊花挥发油(0.8ml/Kg)灌胃给药对2,4-二硝基苯酚致热大鼠体温有明显降温效应;总黄酮(57mg/kg)静脉给药对大鼠血压值有显著降低作用。结论:菊花挥发油解热、总黄酮降压是其散风清热、平肝明目的药理学基础之一。更多还原

【Abstract】 Objective: To study material bases on the antifebirle and hypotensive effect of Flos Chrysanthemi. Methods: Temperature and blood pressure of rats were measured after treatment by taking several kinds of extracts of Flos Chrysanthemi. Results: After volatile oil of Flos Chrysanthemi (0.8 ml/Kg) was taken by oral administration, temperature on the fever heat of rats could be decreased distinctly. After total flavonid of Flos Chrysanthemi (57 mg/Kg) was injected, blood pressure on rats could be reduced remarkly. Conclusion: Volatile oil of Flos Chrysanthemi has antifebrile effect and total flavonid of Flos Chrysanthemi has hypotensive effect, which are one of the Pharmacological bases of dispelling the wind-evil, clearing away the heat-evil, calming the liver, sharping eyes of Flos Chrysanthemi.更多还原