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复方丹参降香的超临界CO2萃取研究

Studies on the Supercritical-CO2 Fluid Extraction of Complex Prescription Danshen-Jiangxiang

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【作者】 葛发欢林秀仙黄晓芬谢健鸣李菁史庆龙

【Author】 Ge Fahuan,Lin Xiuxian,Huang Xiaofeng,Xie Jianming.Li Jing.Shi Qinglong (Guangzhou Pharmaceutical Industrial Research Institute,Guangzhou 510240)

【机构】 广州市医药工业研究所广州市医药工业研究所 广州 510204广州 510204广州 510204

【摘要】 本文首次报道了复方丹参降香的超临界CO2萃取。以有效成分、收率等为指标,研究了复方中药超临界CO2萃取过程中各单味药之间的相互影响及其对整个复方提取的影响,同时也研究了萃取压力和温度的影响。结果证明,复方丹参降香的超临界CO2萃取,其效果完全不同于单味丹参和单味降香的提取:复方提取时,虽然有效成分均能被提取,但它们之间存在较大的相互影响,并共同影响整个复方提取的收率、有效成分的萃出率及其含量等;萃取条件不同,其影响程度不同。本研究结果对于中药复杂体系的研究及其中药现代化具有重要的参考价值。

【Abstract】 This paper first reported the supercritical-CO2 fluid extraction of complex prescription Danshen-Jiangxiang. With the active constituents and yield of extracts as index, the each other effect of each drug and effect on total complex prescription in extraction were studied. And the effects of pressure and temperature were also studied.The results showed the effects were different in complex prescription extraction and single prescription. Active constituents can be extracted,but a obvious effect exist each other and effects togther the yield of extract, extraction rate and content of active constituents of complex prescription extractiion, which are comcerned in extraction conditions. These study results have important reference on the modernization of traditional Chinese medicines.

  • 【文献出处】 中药材 ,Journal of Chinese Medicinal Materials , 编辑部邮箱 ,2001年01期
  • 【分类号】R284
  • 【被引频次】21
  • 【下载频次】285
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