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七叶皂甙对高血压脑出血患者脑血流量的影响

Effect of β-aescin natrum on cerebral blood flow in patients with cerebral hemorrhage induced by hypertension

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【作者】 李飞谷德祥吕忻江施九妹

【Author】 LI Fei,GU Dexiang,LU Xinjiang,et al.ShiDong Hospital of Yangpu District,Shanghai 200090

【机构】 上海市杨浦区市东医院!上海200090

【摘要】 目的 :研究七叶皂甙治疗高血压脑出血的疗效和对患者脑血流量的影响。方法 :70例脑出血患者随机分为 2组 (各 35例 )。对照组常规治疗 ,治疗组加用七叶皂甙 2 0 m g溶于生理盐水 5 0 0 ml中静滴 ,每日 1次 ,共 10日。 2组降压、抗感染等治疗相同。治疗前及 3周后均测定患者的脑血流量和血液流变学变化。结果 :治疗 3周后 ,治疗组总有效率 (94.3% )高于对照组 (77.1% ) ,P<0 .0 5 ;2组脑血流量和血液流变性虽均明显改善 ,但以七叶皂甙组尤佳 ,且颅内血肿吸收优于对照组。结论 :七叶皂甙可有效治疗高血压脑出血

【Abstract】 Objective:To study the influence of βaescin natrum on cerebral blood flow(CBF) in patients with cerebral hemorrhage and the curative effects.Methods:Seventy cases with acute cerebral hemorrhage were randomly divided into two groups.The control group(n=35) was treated with conventional therapy while the treatment group(n=35) based on the same therapy as control group the βaescin natrum 20 mg+normal saline 500 ml infused intravenously once a day were used for 10 days.In addition the same hypotensive,hypoglycemic and antiinfectious therapies were given to both groups.Before and after therapy the volume of CBF and the blood rheology were detected.Results:After 3 weeks therapy the total effective rate was 94.3% in treatment group but it was 77.1% in control group.In comparison between two groups the difference was significant(P<0.05).The volume of CBF and blood rheology in both two groups showed obvious improvements but in treatment group they were the best.Conclusions:The treatment with βaescin natrum combined with conventional therapy for cerebral hemorrhage is superior to that with conventional therapy alone.

  • 【文献出处】 中国中西医结合急救杂志 ,Integrated Traditional Chinese and Western Medicine In Practice of Critical Care Medicine , 编辑部邮箱 ,2001年02期
  • 【分类号】R743.34
  • 【被引频次】21
  • 【下载频次】45
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