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多巴胺和维生素B12球后注射治疗儿童弱视

Clinical study on the treatment of amblyopic children with podamine and vitamin B12 by retrobulbar injection

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【作者】 高丽芬; 房学军; 徐春香;

【Author】 GAO Li fen,FANG Xue jun,XU Chun xiang. Tangshan Ophthalmic Hospital, Tangshan 063000 [FK(WB80011?5]

【机构】 河北省唐山市眼科医院; 河北省唐山市眼科医院 河北唐山063000; 河北唐山063000; 河北唐山063000;

【摘要】 目的 :探讨多巴胺和维生素B12 球后注射治疗儿童弱视的疗效。方法 :80例屈光参差性和斜视性弱视儿童随机分为两组 :治疗组 ,应用小剂量 (2~ 4mg)多巴胺和维生素B12 进行球后注射 ;对照组 ,采用综合疗法如光栅、后像及精细作业等训练。两组均遮盖主导眼 ,观察 3~ 2 4个月 ,平均 15 .8个月。结果 :治疗组基本治愈率为 72 .5 % ,47.5 %恢复完善的立体视觉 ,2 7人P VEP潜时缩短。对照组基本治愈率为 2 7.5 % ,立体视觉恢复率为 15 % ,8人P VEP潜时缩短。两组差异具有非常显著性意义。结论 :多巴胺和维生素B12 治疗儿童弱视安全有效

【Abstract】 Objective:To investigate the effect of retrobulbar injections of podamine and vitamin B 12 on the vision of amblyopic children.Methods:80 cases of children with anisometropic and strabismic amblyopia were randomly divided into two groups. Patients in the drug group were treated with small doses(2~4mg) of podamine and vitamin B 12 by retrobulbar injection. Patients in the control group received a comprehensive treatment including visual after image stimulation and a rotating spiral. Both groups had their healthy eyes patched and were observed for a period of about 3~24 months(15.8 months on average).Results:The cure rate in the drug group was 72.5%,with 47.5% obtaining full stereoscopic vision. The corresponding results in the control group were 27.5% and 15%,respectively. Shorter latencies were found in the p 100 wave of the P VEP in 27 cases in the drug group but in only 8 cases in the control group. The difference between the two groups was significant.Conclusion:Injection of podamine and vitamin B 12 is an effective and safe procedure for the treatment of amblyopic children. [FK(WB80011?6]

  • 【文献出处】 眼视光学杂志 ,Journal of Optometry & Ophthalmology , 编辑部邮箱 ,2001年04期
  • 【分类号】R777.44
  • 【被引频次】9
  • 【下载频次】72
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