节点文献
复方犀黄丸含药血清体外抗癌作用的研究
Application of Serologic Pharmacologic Method in the Study of Anti-Carcino Genic Property of Chinese Herbal Mixture Xihuangwan in Vitro
【摘要】 目的 :探讨中药复方犀黄丸对人肝癌细胞体外生长的影响。方法 :制备中药含药血清 ,采用MTT法检测体外培养肝癌细胞的生长抑制率。结果 :犀黄丸含药血清对肝癌细胞生长抑制率达 39%。 10 %、15 %、2 0 %含药血清组对癌细胞的生长抑制率高于对照组及 2 5 %、5 %组 (P <0 0 5 )。其血清浓度与抑制率呈直线相关。结论 :血清药理学方法是研究中药复方抗癌作用的有效方法 ,复方犀黄丸对肝癌细胞体外生长有一定的抑制作用。
【Abstract】 Objective:To investigate the effect of chinese herbal mixture Xihuangwan on the cell growth of liver neoplasm in vitro.Methods:The serologic pharmacological method and MTT assay were used.Results:The suppress rate of cells treated with Xihuangwan was nearly 39%,which were much more higher in 10%,15% and 20% groups than in control,2.5% and 5% groups.There existed a line relation between the concentrations of this herbal mixture and its suppress rate.Conclusion:The serologic pharmacologic method is effective in anti carcinogenic property of Chinese herbal mixture,it has some inhibitory effect on tumor cell proliferation in vitro.
- 【文献出处】 中国中西医结合消化杂志 ,Chinese Journal of Integrated Traditional and Western Medicine On Gastro-spleen , 编辑部邮箱 ,2001年04期
- 【分类号】R273
- 【被引频次】18
- 【下载频次】158