【摘要】 目的　探讨小儿热性惊厥 (FC)的病理形态学基础 ,以进一步探讨 FC的定义及诊断问题。方法　对 410例临床诊断为 FC患儿进行头颅 CT检查 ,其中单纯性 FC(SFC) 2 0 9例 ,复杂性 FC(CFC) 2 0 1例。同时选择了同时期因头部外伤而接受 CT检查的 42 7例作为对照组。结果　对照组 42 7例删除了急性颅脑损伤 CT改变后 ,属原有存在的颅脑形态学异常 6 0例 (14.12 % ) ,SFC组 2 0 9例颅脑 CT异常 75例 (35 .89% ) ,CFC组 2 0 1例颅脑 CT异常 96例 (4 7.76 % ) ,分别与对照组比较 P均 <0 .0 0 5 ,其比数比 (OR)值分别达 3.42和 5 .5 9。 SFC组和 CFC组的颅脑异常主要因为硬膜下积液 (或外部性脑积水、蛛网膜下腔增宽 ) ,共占异常改变的 6 2 .79%。结论　通过头颅 CT检查发现 FC患儿中 ,相当一部分存在明显的脑形态学异常 ,这些脑形态学改变应视为 FC发病的病理基础。更多还原

【Abstract】 Objective To study the pathologic morphology of febrile convulsion(FC) as well as it′s definition and the diagnostic criteria.Methods Brain computer tomography(CT) were performed in 410 cases with FC, comprised 209 cases with sim ple febrile convulsion(SFC) and 201 with complicated febrile convulsion (CFC). 4 27 cases with head injury were as control.Results Deleted the i mage changes due to brain damage, we found 60 cases(14.12%) with original brain paramorphia in c ontrol group. While 75 cases (35.89%) with abnormal CT image in SFC group and 96 cases (47.76%) in CFC group. The control group showed significant differences o f the abnormal rate compared with SFC group as well as CFC group (P<0.005).The OR were 3.42 and 5.59.The top kinds of abnormalities in SFC gro up and CFC group were listed as subdural effusion (or external hydrocephalus, wi dened subarachnoid cavity),account for 62.79% in all.Conclusion A considerable number of FC patients were found marked abnormalities of brain morphology via C T examination. They can be considered as the pathologic bases of FC.更多还原