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阵发性心房颤动者心房内及房室结电生理特性

Study on Electrophysiological Properties of Atrial and Atrioventricular Node in Patients with Paroxysmal Atrial Fibrillation

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【作者】 高修仁刘思明马虹柳俊王业松梁耀荣

【Author】 GAO Xiu-ren, LIU Si-ming, MA Hong, LIU Jun, WANG Ye-song, LIANG Yao-rong (Department of Cardiology Heart Center, the First Affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou 510080, China)$$$$

【机构】 中山医科大学附属第一医院心内科!广东广州510080中山医科大学附属第一医院?

【摘要】 【目的】比较阵发性心房颤动 (简称阵发性房颤 )者及正常人心房内及房室结的电生理特性差异 ,通过调搏刺激研究两者的房颤诱发成功率。【方法】用食道心房调搏技术对 182例阵发性房颤者及 30例健康成年人进行程序刺激并作电生理测定。【结果】①食道心房调搏术对阵发性房颤者的诱发成功率高达 95 6 % ;②窦律及基础起搏情况下两组的房内传导及房室传导无统计学差别 ;③早搏刺激下阵发性房颤者以心房有效不应期缩短、相对不应期延长、及房间传导时间延长为主要特点 ,与正常人比较有高度显著性差异。【结论】①房颤患者这些电生理异常有利于房颤时微小折返的形成 ;②对于临床高度怀疑房颤但又缺乏心电图证据的患者食道心房调搏术有助于诊断的确立。

【Abstract】 Objective To compare the difference of electrophysiological properties in atrial and atrioventricular node between patients with paroxysmal atrial fibrillation and normal adults, and to study the initiation rate of atrial fibrillation in the two groups. Methods The electrophysiological preperties were detected by the technique of esophagus-atrial program pacing in 182 patients with paroxysmal atrial fibrillation and 30 normal adults. Result ①The initiation rate of atrial fibrillation by the technique of esophagus-atrial pacing was 95.6%; ②In the state of normal sinus rhythm and in basic cycle length, There was no difference in atrial and A-V node conduction function between the two groups; ③The atrial effective refrectory period (ERP A) was significantly shortened and both atrial relative refrectory period (RRP A) and intra-atrial conduction delay (IACD) were significantly lengthened in the atrial fibrillation group when compared with the control group by using premature impulse. Conclusion ①In patients with atrial fibrillation, the abnormalities of electrophysiological property would favor the development of micro-circus movement; ②The esophagus-atrial pacing may be the useful method for identifing the clinical diagnosis of suspected atrial fibrillation but short of evidence of eletrocardiogram.

【基金】 广东省卫生厅基金资助项目! (1996年 )
  • 【文献出处】 中山医科大学学报 ,Academic Journal of Sun Yat-sen University of Medical Sciences , 编辑部邮箱 ,2001年01期
  • 【分类号】R541.7
  • 【被引频次】6
  • 【下载频次】46
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