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心磷脂抗体与缺血性脑血管病

Analysis Anti-cardiolipin Antibodies in Ischemic Cerebrovascular Diseases

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【作者】 高德琴艾桂萍刘添翼罗盛刘向祎

【Author】 GAO De qin 1, AI Gui ping 1, LIU Tian yi 1, LUO Sheng 2, LIU Xiang yi 3(1. Laboratory of Medicine, 2. Department of Neurology, Beijing Hospital , Ministry of Health, Beijing 100730; 3.Laboratory of Medicine,Tongren Hospital, Beijing 100730,Chi

【机构】 卫生部北京医院检验科免疫室!北京100730卫生部北京医院神经内科!北京100730同仁医院检验科!北京100730

【摘要】 目的 建立测定血清心磷脂抗体 (A-CL)的方法 ,研究 A-CL与缺血性脑血管病的关系。方法 建立心磷脂抗体的 ELISA检测方法 ,对 4 2例健康者和 85例缺血性脑血管病、其他神经系统疾病患者血清 A-CL(Ig G、Ig M)进行测定。结果  51例缺血性脑血管病中 ,1 1例 A-CL Ig G阳性 ,5例 A-CL Ig M阳性 ,脑出血及其他神经系统疾病均为阴性。结论 心磷脂抗体与缺血性脑血管病密切相关

【Abstract】 Objective By determining serum cardiolipin antibodies(A CL) to explore the relation of autoantibody and ischemic cerebrovascular diseases.Methods Serum A CL(IgG,IgM) were determined by (ELISA),85 patient sera with ischemic cerebrovascular disease, cerebrovascular hemorrhages, GBS, Hallervorden spatz were evaluated and comparied with 42 normal peoples. Results In 51 ischemic cerebrovascular disease patients,11 patients were A CL IgG positive, and 5 patients showed A CL IgM positive. All of cerebrovascular bleeding and other neurologic disease patients was A CL negative.Conclusions Serum A CL were strongly related to ischemic cerebrovascular disease . This results suggests that A CL may be a associated factor of ischemic cerebrovascular disease.

  • 【文献出处】 中国神经免疫学和神经病学杂志 ,Chinese Journal of Neuroimmunlolgy and Neurology , 编辑部邮箱 ,2001年03期
  • 【分类号】R743
  • 【被引频次】1
  • 【下载频次】31
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