【摘要】 目的　研究早产儿视网膜病 (ROP)的患病率、高危因素、治疗及随访预后。方法　对 1996～ 2 0 0 0年 5年中住院的 5 6 8例早产儿常规行眼底检查至生后 6个月 ,发现ROP者密切随访追踪 ,Ⅲ期阈值以上者行激光或冷凝手术治疗。结果　检出ROP患儿 46例 (8 1% ) ,其中 2 3例 (5 0 0 % )病变逐渐稳定并恢复正常 ;8例(17 4% )病情进展恶化需手术治疗 ;8例 (17 4% )有持续局限性病变 ,视力明显受损 ;3例 (6 5 % )失明 ,4例失访。高危因素分别为低出生体重、小孕周、长期或高浓度氧疗以及早期严重贫血。结论　ROP严重影响早产儿远期生存质量 ,建议对所有早产儿及有高危因素的新生儿常规行眼底检查 ,以早期发现ROP并给予适当治疗及随访更多还原

【Abstract】 Objective\ To study the incidence?high risk factors?treatment and follow up in the infants with retinopathy of prematurity(ROP).Methods\ Regular eye examinations were performed on 568 premature infants during 1996～2000,repeated check every two weeks until 6 months after birth.For those babies with ROP,continue to follow up to see if they need treatment until 3 years later.Results\ 46 premature infants were found with ROP,incidence was 8 1%.In 23(50%) cases,the ROP regressed spontaneously during stage 1～3;In 8(17 3%)cases,ROP progressed to advanced stages and had to be performed laser treatment or cryotherapy;8(17 3%)cases had persisted localized pathologic changes and with poor visual capacity;3(6 5%) cases developed to blind.The high risk factors were low birth weight,small gestational age,long term oxygen therapy and early severe anemia.Conclusion\ All premature infants and the newborn with high risk factors should take regular ophthalmic examination in order to detect early ROP and follow up or have required treatment.更多还原