【摘要】 以我国狂犬病固定毒人二倍体细胞适应株 (CTN - 1)作Vero细胞适应传代研究。显示CTN - 1株能较好适应Vero细胞 ,经 5代培养病毒滴度可达 7 5logLD5 0 /ml,且在 5～ 2 0代以内均稳定在 7 0logLD5 0 /ml左右 ,符合WHO对生产用毒种滴度要求更多还原

【Abstract】 The culture conditions and passage methods of attenuated fixed rabies virus strain CTN-1 in vero cells were studied in this paper.The results showed that the CTN-1 rabies virus stratins can be well adapted in vero cell cultures.The titer of CTN-1 strain was reached to 7.5logLD50/ml after 5 passages in vero cells,which met the standard by WHO’S reguremant.更多还原