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西沙必利对健康志愿者胆囊排空的作用
Effects of cisapride on gallbladder emptying in the healthy volunteers
【摘要】 目的:了解西沙必利对健康人类胆囊张力及餐后胆囊排空的影响。方法:应用B型超声仪测定了15 例健康志愿者服用西沙必利前后的空腹和餐后的胆囊容积,并计算其对胆囊排空率的影响。结果:15例健康志愿者口服西沙必利前、后空腹胆囊的容积无明显改变 (P>0.05)。服用西沙必利后的餐后30min胆囊容积较服西沙必利前明显缩小(P<0.05)。服西沙必利后胆囊排空率显著增加 (P<0.001)。 结论:西沙必利对空腹胆囊容积无明显影响,但可显著促进餐后胆囊的收缩及排空。
【Abstract】 Objective: To study effects of cisapride on the human gallbladder volume and emptying. Methods: Fasting and postprandial gallbladder volumes were measured with ultrasonography in 15 healthy volunteers before and after taking cisapride orally. Gallbladder volumes were normalized to gallbladder ejection frequency (GBEF). Results: The fasting gallbladder volume in 15 healthy subjects did not change before or after cisapride administration (P>0.05). Postprandial gallbladder volume 30min after taking became smaller than that before taking cisapride (P<0.05). GBEF was significantly enhanced that after cisapride administration(P<0.001). Conclusion: Cisapride had no effect on the fasting gallbladder volumes but significantly promoted postprandial gallbladder contraction and emptying.
- 【文献出处】 重庆医科大学学报 ,Acta Universitatis Scientiae Medicinae , 编辑部邮箱 ,2001年02期
- 【分类号】R969
- 【被引频次】5
- 【下载频次】14