【摘要】 目的：对慢性DHBV感染鸭的肝、胰、脾组织 DHBV DNA作对比研究。方法：采用原位杂交技术。结果：DHBV不仅可以感染鸭肝细胞，且可感染胰、脾组织，DHBV DNA 阳性细胞的分布密度以肝组织最高，胰脾次之。结论：DHBV具有组织器官泛嗜性，但其在肝外组织中的复制似不及在肝细胞中活跃。更多还原

【Abstract】 Objective: To study the difference of DHBV DNA in the duck’s liver, pancreas and spleen tissue. Methods : In situ hybridization using digoxigenin-labeled DHBV DNA C gene probe. Results: DHBV DNA was present not only in hepatocytes but also in the pancreatic acini , in cells of splenic red pulp and in the splenic germinal center. The DHBV DNA positive cells appeared more frequently in liver than in spleen and pancreas. Conclusion: It suggests that DHBV is also tropic for extrahepatic tissue, but it may replicate more actively in liver than in the extrahepatic tissue.更多还原