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甲胎蛋白低浓度阳性肝细胞癌

Heptocellular carcinoma with serum AFP level in 21μg/L to 200 μg/L

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【作者】 张建淮王建营马曾辰

【Author】 ZHANG Jian-huai1, WANG Jian-ying1, MA Zeng-chen2 (1.Department of General Surgery, The Second People’s Hospital of Huaiyin City, Huaiyin, Jiangsu 223002, China; 2.Department of Liver Cancer, Affiliated Zhongshan Hospital, Fudan University Medical School,

【机构】 江苏省淮阴市第二人民医院普外科!江苏淮阴223002复旦大学医学院中山医院肝肿瘤科!上海200032

【摘要】 目的 介绍甲胎蛋白 (AFP)低浓度阳性肝细胞癌 (HCC)的临床诊断特点。方法 复习相关文献 ,作综合性报道。结果与结论  (1)在有肝实质占位病变 (SOL)存在时 ,AFP低浓度升高可作为诊断HCC的参考标准 ;(2 )提出低浓度AFPHCC ,有助于避免AFP 2 1 2 0 0 μg/L之间HCC的漏诊 ,利于在AFP较低浓度时作出早期诊断 ;(3 )用AFP >2 0 μg/L结合B超、CT等检查联合进行诊断 ,提高了单一诊断手段的敏感性和特异性

【Abstract】 Objective To introduce clinical diagnostic specificity of hepatocellular carcinoma (HCC) with serum AFP level in 21*!μg/L to 200*!μg/L. Methods Making a literature summarizaton based on the papers review.Results and Conclusions (1) The AFP level more than 20*!μg/L can be used as a diagnostic criteria of HCC when existing liver space occuping lesion (SOL). (2) The clinical diagnostic criteria using AFP level more than 20 μg/L instead of more than 200 μg/L would be helpful to avoid misdiagnosis of HCC with the AFP level in 21 μg/L to 200 μg/L. (3) The Combination of AFP level more than 20 μg/L with ultrasonography, CT scanning would have higher sensitivity and specificity than single diagnostic method.

  • 【文献出处】 中国普通外科杂志 ,Chinese Journal of General Surgery , 编辑部邮箱 ,2001年02期
  • 【分类号】R735.7
  • 【被引频次】7
  • 【下载频次】74
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